Quantitative Proteomics and Differential Protein Abundance Analysis after Depletion of Putative mRNA Receptors in the ER Membrane of Human Cells Identifies Novel Aspects of mRNA Targeting to the ER

In human cells, one-third of all polypeptides enter the secretory pathway at the endoplasmic reticulum (ER). The specificity and efficiency of this process are guaranteed by targeting of mRNAs and/or polypeptides to the ER membrane. Cytosolic SRP and its receptor in the ER membrane facilitate the co...

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Detalles Bibliográficos
Autores principales: Bhadra, Pratiti, Schorr, Stefan, Lerner, Monika, Nguyen, Duy, Dudek, Johanna, Förster, Friedrich, Helms, Volkhard, Lang, Sven, Zimmermann, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230838/
https://www.ncbi.nlm.nih.gov/pubmed/34208277
http://dx.doi.org/10.3390/molecules26123591

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