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Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013

Sinularia is one of the conspicuous soft coral species widely distributed in the world’s oceans at a depth of about 12 m. Secondary metabolites from the genus Sinularia show great chemical diversity. More than 700 secondary metabolites have been reported to date, including terpenoids, norterpenoids,...

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Detalles Bibliográficos
Autores principales: Yan, Xia, Liu, Jing, Leng, Xue, Ouyang, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230912/
https://www.ncbi.nlm.nih.gov/pubmed/34208171
http://dx.doi.org/10.3390/md19060335
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author Yan, Xia
Liu, Jing
Leng, Xue
Ouyang, Han
author_facet Yan, Xia
Liu, Jing
Leng, Xue
Ouyang, Han
author_sort Yan, Xia
collection PubMed
description Sinularia is one of the conspicuous soft coral species widely distributed in the world’s oceans at a depth of about 12 m. Secondary metabolites from the genus Sinularia show great chemical diversity. More than 700 secondary metabolites have been reported to date, including terpenoids, norterpenoids, steroids/steroidal glycosides, and other types. They showed a broad range of potent biological activities. There were detailed reviews on the terpenoids from Sinularia in 2013, and now, it still plays a vital role in the innovation of lead compounds for drug development. The structures, names, and pharmacological activities of compounds isolated from the genus Sinularia from 2013 to March 2021 are summarized in this review.
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spelling pubmed-82309122021-06-26 Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013 Yan, Xia Liu, Jing Leng, Xue Ouyang, Han Mar Drugs Review Sinularia is one of the conspicuous soft coral species widely distributed in the world’s oceans at a depth of about 12 m. Secondary metabolites from the genus Sinularia show great chemical diversity. More than 700 secondary metabolites have been reported to date, including terpenoids, norterpenoids, steroids/steroidal glycosides, and other types. They showed a broad range of potent biological activities. There were detailed reviews on the terpenoids from Sinularia in 2013, and now, it still plays a vital role in the innovation of lead compounds for drug development. The structures, names, and pharmacological activities of compounds isolated from the genus Sinularia from 2013 to March 2021 are summarized in this review. MDPI 2021-06-11 /pmc/articles/PMC8230912/ /pubmed/34208171 http://dx.doi.org/10.3390/md19060335 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yan, Xia
Liu, Jing
Leng, Xue
Ouyang, Han
Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013
title Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013
title_full Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013
title_fullStr Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013
title_full_unstemmed Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013
title_short Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013
title_sort chemical diversity and biological activity of secondary metabolites from soft coral genus sinularia since 2013
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230912/
https://www.ncbi.nlm.nih.gov/pubmed/34208171
http://dx.doi.org/10.3390/md19060335
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