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NXP031 Improves Cognitive Impairment in a Chronic Cerebral Hypoperfusion-Induced Vascular Dementia Rat Model through Nrf2 Signaling

Vascular dementia (VaD) is a progressive cognitive impairment caused by a reduced blood supply to the brain. Chronic cerebral hypoperfusion (CCH) is one cause of VaD; it induces oxidative stress, neuroinflammation, and blood-brain barrier (BBB) disruption, damaging several brain regions. Vitamin C p...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Min, Lee, Joo-Hee, Song, Min-Kyung, Kim, Youn-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230952/
https://www.ncbi.nlm.nih.gov/pubmed/34208092
http://dx.doi.org/10.3390/ijms22126285