Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach

SIMPLE SUMMARY: High levels of Heat shock proteins (Hsps) in specific cancers are usually linked to a poor prognosis, tumor progression, invasiveness, and resistance to treatment. Chaperone inhibition could therefore be toxic for cancer cells due to their high dependence on chaperone activity to sur...

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Detalles Bibliográficos
Autores principales: Dublang, Leire, Underhaug, Jarl, Flydal, Marte I., Velasco-Carneros, Lorea, Maréchal, Jean-Didier, Moro, Fernando, Boyano, Maria Dolores, Martinez, Aurora, Muga, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230956/
https://www.ncbi.nlm.nih.gov/pubmed/34208232
http://dx.doi.org/10.3390/cancers13122936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230956/
https://www.ncbi.nlm.nih.gov/pubmed/34208232
http://dx.doi.org/10.3390/cancers13122936

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