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Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach
SIMPLE SUMMARY: High levels of Heat shock proteins (Hsps) in specific cancers are usually linked to a poor prognosis, tumor progression, invasiveness, and resistance to treatment. Chaperone inhibition could therefore be toxic for cancer cells due to their high dependence on chaperone activity to sur...
Autores principales: | Dublang, Leire, Underhaug, Jarl, Flydal, Marte I., Velasco-Carneros, Lorea, Maréchal, Jean-Didier, Moro, Fernando, Boyano, Maria Dolores, Martinez, Aurora, Muga, Arturo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230956/ https://www.ncbi.nlm.nih.gov/pubmed/34208232 http://dx.doi.org/10.3390/cancers13122936 |
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