Metabolic features of cancer cells impact immunosurveillance

BACKGROUND: Tumors rewire their metabolism to achieve robust anabolism and resistance against therapeutic interventions like cisplatin treatment. For example, a prolonged exposure to cisplatin causes downregulation of pyridoxal kinase (PDXK), the enzyme that generates the active vitamin B6, and upre...

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Detalles Bibliográficos
Autores principales: Joseph, Adrien, Juncheng, Pan, Mondini, Michele, Labaied, Nizar, Loi, Mauro, Adam, Julien, Lafarge, Antoine, Astesana, Valentina, Obrist, Florine, Klein, Christophe, Bloy, Norma, Stoll, Gautier, Signolle, Nicolas, Genestie, Catherine, Damotte, Diane, Alifano, Marco, Leary, Alexandra, Pautier, Patricia, Morice, Philippe, Gouy, Sebastien, Deutsch, Eric, Chargari, Cyrus, Dieu-Nosjean, Marie-Caroline, Cremer, Isabelle, Michels, Judith, Kroemer, Guido, Castedo, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231002/
https://www.ncbi.nlm.nih.gov/pubmed/34162714
http://dx.doi.org/10.1136/jitc-2021-002362

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