Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children (SchistoSAM): protocol of a proof-of-concept, open-label, two-arm, individually-randomised controlled trial

INTRODUCTION: Alternative drugs and diagnostics are needed for the treatment and control of schistosomiasis. The exclusive use of praziquantel (PZQ) in mass drug administration programmes may result in the emergence of drug resistance. PZQ has little activity against Schistosoma larvae, thus reinfec...

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Detalles Bibliográficos
Autores principales: Roucher, Clémentine, Brosius, Isabel, Mbow, Moustapha, Faye, Babacar Thiendella, De Hondt, Annelies, Smekens, Bart, Arango, Diana, Burm, Christophe, Tsoumanis, Achilleas, Paredis, Linda, van Herrewege, Yven, Potters, Idzi, Cisse, Badara, Mboup, Souleymane, Polman, Katja, Bottieau, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Infectious Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231067/
https://www.ncbi.nlm.nih.gov/pubmed/34168029
http://dx.doi.org/10.1136/bmjopen-2020-047147

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