Optimization of Tabersonine Methoxylation to Increase Vindoline Precursor Synthesis in Yeast Cell Factories

Plant specialized metabolites are widely used in the pharmaceutical industry, including the monoterpene indole alkaloids (MIAs) vinblastine and vincristine, which both display anticancer activity. Both compounds can be obtained through the chemical condensation of their precursors vindoline and cath...

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Detalles Bibliográficos
Autores principales: Lemos Cruz, Pamela, Kulagina, Natalja, Guirimand, Grégory, De Craene, Johan-Owen, Besseau, Sébastien, Lanoue, Arnaud, Oudin, Audrey, Giglioli-Guivarc’h, Nathalie, Papon, Nicolas, Clastre, Marc, Courdavault, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231165/
https://www.ncbi.nlm.nih.gov/pubmed/34208368
http://dx.doi.org/10.3390/molecules26123596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231165/
https://www.ncbi.nlm.nih.gov/pubmed/34208368
http://dx.doi.org/10.3390/molecules26123596

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