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Optimization of Tabersonine Methoxylation to Increase Vindoline Precursor Synthesis in Yeast Cell Factories
Plant specialized metabolites are widely used in the pharmaceutical industry, including the monoterpene indole alkaloids (MIAs) vinblastine and vincristine, which both display anticancer activity. Both compounds can be obtained through the chemical condensation of their precursors vindoline and cath...
Autores principales: | Lemos Cruz, Pamela, Kulagina, Natalja, Guirimand, Grégory, De Craene, Johan-Owen, Besseau, Sébastien, Lanoue, Arnaud, Oudin, Audrey, Giglioli-Guivarc’h, Nathalie, Papon, Nicolas, Clastre, Marc, Courdavault, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231165/ https://www.ncbi.nlm.nih.gov/pubmed/34208368 http://dx.doi.org/10.3390/molecules26123596 |
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