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Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets

The development of DNA microarray and RNA-sequencing technology has led to an explosion in the generation of transcriptomic differential expression data under a wide range of biologic systems including those recapitulating the monogenic muscular dystrophies. Data generation has increased exponential...

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Detalles Bibliográficos
Autores principales: Hadwen, Jeremiah, Schock, Sarah, Farooq, Faraz, MacKenzie, Alex, Plaza-Diaz, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231191/
https://www.ncbi.nlm.nih.gov/pubmed/34208365
http://dx.doi.org/10.3390/ijms22126295