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Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets
The development of DNA microarray and RNA-sequencing technology has led to an explosion in the generation of transcriptomic differential expression data under a wide range of biologic systems including those recapitulating the monogenic muscular dystrophies. Data generation has increased exponential...
Autores principales: | Hadwen, Jeremiah, Schock, Sarah, Farooq, Faraz, MacKenzie, Alex, Plaza-Diaz, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231191/ https://www.ncbi.nlm.nih.gov/pubmed/34208365 http://dx.doi.org/10.3390/ijms22126295 |
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