Cargando…

Pioglitazone Ameliorates Lipopolysaccharide-Induced Behavioral Impairment, Brain Inflammation, White Matter Injury and Mitochondrial Dysfunction in Neonatal Rats

Previous studies have demonstrated that pioglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, inhibits ischemia-induced brain injury. The present study was conducted to examine whether pioglitazone can reduce impairment of behavioral deficits mediated by inflammatory-indu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yeh, Jiann-Horng, Wang, Kuo-Ching, Kaizaki, Asuka, Lee, Jonathan W., Wei, Han-Chi, Tucci, Michelle A., Ojeda, Norma B., Fan, Lir-Wan, Tien, Lu-Tai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231261/ https://www.ncbi.nlm.nih.gov/pubmed/34208374 http://dx.doi.org/10.3390/ijms22126306

Ejemplares similares

Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide
por: Kaizaki, Asuka, et al.
Publicado: (2013)

Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats
por: Hsieh, Cheng-Ta, et al.
Publicado: (2018)

Erythropoietin Ameliorates Neonatal Hypoxia-Ischemia-Induced Neurobehavioral Deficits, Neuroinflammation, and Hippocampal Injury in the Juvenile Rat
por: Lan, Kuo-Mao, et al.
Publicado: (2016)

Interleukin-1 Receptor Antagonist Reduces Neonatal Lipopolysaccharide-Induced Long-Lasting Neurobehavioral Deficits and Dopaminergic Neuronal Injury in Adult Rats
por: Pang, Yi, et al.
Publicado: (2015)

Oxidative Stress and Neurodevelopmental Outcomes in Rat Offspring with Intrauterine Growth Restriction Induced by Reduced Uterine Perfusion
por: Rains, Marcelo E., et al.
Publicado: (2021)

TNF-α antagonist attenuates systemic lipopolysaccharide-induced brain white matter injury in neonatal rats
por: Shin, Seung Han, et al.
Publicado: (2019)

Pioglitazone Enhances Cytosolic Lipolysis, β-oxidation and Autophagy to Ameliorate Hepatic Steatosis
por: Hsiao, Pi-Jung, et al.
Publicado: (2017)

The Ameliorative Effect of Pioglitazone against Neuroinflammation Caused by Doxorubicin in Rats
por: Alsaud, May M., et al.
Publicado: (2023)

Intracerebral lipopolysaccharide induces neuroinflammatory change and augmented brain injury in growth-restricted neonatal rats
por: Campbell, Leigh R., et al.
Publicado: (2012)

Pioglitazone Ameliorates Neuron Loss in the Cortex after Aluminum-Treatment in Rats
por: Rafati, Ali, et al.
Publicado: (2015)

Pioglitazone Ameliorates Acute Endotoxemia-Induced Acute on Chronic Renal Dysfunction in Cirrhotic Ascitic Rats
por: Liu, Szu-Yu, et al.
Publicado: (2021)

Parental age effects on neonatal white matter development
por: Gale-Grant, Oliver, et al.
Publicado: (2020)

Pioglitazone ameliorates the phenotype of a novel Parkinson’s disease mouse model by reducing neuroinflammation
por: Pinto, Milena, et al.
Publicado: (2016)

Stochastic process for white matter injury detection in preterm neonates()
por: Cheng, Irene, et al.
Publicado: (2015)

Neonatal White Matter Maturation Is Associated With Infant Language Development
por: Sket, Georgina M., et al.
Publicado: (2019)

Pioglitazone Ameliorates Gentamicin Ototoxicity by Affecting the TLR and STAT Pathways in the Early Postnatal Organ of Corti
por: Sekulic-Jablanovic, Marijana, et al.
Publicado: (2020)

Guanabenz ameliorates disease in vanishing white matter mice in contrast to sephin1
por: Witkamp, Diede, et al.
Publicado: (2022)

Pioglitazone: Indian perspective
por: Shukla, Rishi, et al.
Publicado: (2011)

Melatonin Promotes Oligodendroglial Maturation of Injured White Matter in Neonatal Rats
por: Olivier, Paul, et al.
Publicado: (2009)

Motor function and white matter connectivity in children cooled for neonatal encephalopathy
por: Spencer, Arthur P.C., et al.
Publicado: (2021)

Placental transcriptional signatures associated with cerebral white matter damage in the neonate
por: Marable, Carmen Amelia, et al.
Publicado: (2022)

Multi-Hit White Matter Injury-Induced Cerebral Palsy Model Established by Perinatal Lipopolysaccharide Injection
por: Liu, Le, et al.
Publicado: (2022)

Early Postnatal Lipopolysaccharide Exposure Leads to Enhanced Neurogenesis and Impaired Communicative Functions in Rats
por: Pang, Yi, et al.
Publicado: (2016)

Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus
por: Wang, Yao, et al.
Publicado: (2017)

Combined therapy with pioglitazone and FGF21 mRNA synergistically ameliorates metabolic disorders in NAFLD rats
por: Huang, Xixia, et al.
Publicado: (2023)

Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
por: Forbes, Thomas A., et al.
Publicado: (2020)

Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin
por: van Wageningen, Thecla A., et al.
Publicado: (2021)

Correction: Melatonin Promotes Oligodendroglial Maturation of Injured White Matter in Neonatal Rats
por: Olivier, Paul, et al.
Publicado: (2009)

Interaction of Inflammation and Hyperoxia in a Rat Model of Neonatal White Matter Damage
por: Brehmer, Felix, et al.
Publicado: (2012)

Altered white matter and cortical structure in neonates with antenatally diagnosed isolated ventriculomegaly
por: Lockwood Estrin, G., et al.
Publicado: (2016)

White Matter Microstructural Integrity and Neurobehavioral Outcome of HIV-Exposed Uninfected Neonates
por: Tran, Linh T., et al.
Publicado: (2016)

White matter injury after neonatal encephalopathy is associated with thalamic metabolite perturbations
por: Montaldo, Paolo, et al.
Publicado: (2020)

Maternal depressive symptoms, neonatal white matter, and toddler social-emotional development
por: Lautarescu, Alexandra, et al.
Publicado: (2022)

Pioglitazone-Induced Acute Rhabdomyolysis
por: Slim, Raoudha, et al.
Publicado: (2009)

Investigation of the antibacterial activity of pioglitazone
por: Masadeh, Majed M, et al.
Publicado: (2011)

Usage of pioglitazone at Medanta, the Medicity
por: Mithal, Ambrish, et al.
Publicado: (2014)

Pioglitazone: A prudent prescription
por: Kalra, Sanjay, et al.
Publicado: (2013)

Reassessment of Pioglitazone for Alzheimer’s Disease
por: Saunders, Ann M., et al.
Publicado: (2021)

Weight reduction and pioglitazone ameliorate polycystic ovary syndrome after removal of a Sertoli-stromal cell tumor
por: Baba, Tsuyoshi, et al.
Publicado: (2012)

Pioglitazone Ameliorates Atorvastatin-Induced Islet Cell Dysfunction through Activation of FFA1 in INS-1 Cells
por: Zhu, Kongbo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j2gj3bh809mmdbbb4ef7k8r2bo