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Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?

BACKGROUND: A defining characteristic of dystonia is its position-dependence. In cervical dystonia (CD), sensory tricks ameliorate head tremor (HT). But it remains unknown whether raising the arms alone has the same impact. METHODS: We analyzed data collected from patients enrolled by the Dystonia C...

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Autores principales: Cisneros, Elizabeth, Vu, Jeanne P., Lee, Ha Yeon, Chen, Qiyu, Benadof, Casey N., Zhang, Zheng, Pettitt, Emily A., Joshi, Subhagya K., Barbano, Richard L., Jankovic, Joseph, Jinnah, Hyder A., Perlmutter, Joel S., Berman, Brian D., Mahajan, Abhimanyu, Goetz, Christopher G., Stebbins, Glenn T., Comella, Cynthia L., Peterson, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231450/
https://www.ncbi.nlm.nih.gov/pubmed/34221696
http://dx.doi.org/10.5334/tohm.623
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author Cisneros, Elizabeth
Vu, Jeanne P.
Lee, Ha Yeon
Chen, Qiyu
Benadof, Casey N.
Zhang, Zheng
Pettitt, Emily A.
Joshi, Subhagya K.
Barbano, Richard L.
Jankovic, Joseph
Jinnah, Hyder A.
Perlmutter, Joel S.
Berman, Brian D.
Mahajan, Abhimanyu
Goetz, Christopher G.
Stebbins, Glenn T.
Comella, Cynthia L.
Peterson, David A.
author_facet Cisneros, Elizabeth
Vu, Jeanne P.
Lee, Ha Yeon
Chen, Qiyu
Benadof, Casey N.
Zhang, Zheng
Pettitt, Emily A.
Joshi, Subhagya K.
Barbano, Richard L.
Jankovic, Joseph
Jinnah, Hyder A.
Perlmutter, Joel S.
Berman, Brian D.
Mahajan, Abhimanyu
Goetz, Christopher G.
Stebbins, Glenn T.
Comella, Cynthia L.
Peterson, David A.
author_sort Cisneros, Elizabeth
collection PubMed
description BACKGROUND: A defining characteristic of dystonia is its position-dependence. In cervical dystonia (CD), sensory tricks ameliorate head tremor (HT). But it remains unknown whether raising the arms alone has the same impact. METHODS: We analyzed data collected from patients enrolled by the Dystonia Coalition. For 120 patients with HT, we assessed how raising their arms without touching their head changed their HT severity. RESULTS: Forty-eight out of 120 patients exhibited changes in HT severity when raising their arms. These patients were more likely to exhibit decreases in HT severity (N = 35) than increases (N = 13, χ(2) (1, N = 48) = 10.1, p = 0.002). Demographic factors and sensory trick efficacy were not significant predictors of whether HT severity changed when raising their arms. DISCUSSION: Raising the arms without touching the head is a posture that can reduce HT severity in some CD patients. Our results extend the concept of position-dependent motor symptoms in CD to include the position of the arms. HIGHLIGHTS: Head tremor (HT) is a prevalent symptom of cervical dystonia (CD) that can often be disabling. This study demonstrates that raising the arms without touching the head is a posture that can reduce HT severity in some CD patients. Our findings also identify a novel form of position-dependence in CD.
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spelling pubmed-82314502021-07-01 Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia? Cisneros, Elizabeth Vu, Jeanne P. Lee, Ha Yeon Chen, Qiyu Benadof, Casey N. Zhang, Zheng Pettitt, Emily A. Joshi, Subhagya K. Barbano, Richard L. Jankovic, Joseph Jinnah, Hyder A. Perlmutter, Joel S. Berman, Brian D. Mahajan, Abhimanyu Goetz, Christopher G. Stebbins, Glenn T. Comella, Cynthia L. Peterson, David A. Tremor Other Hyperkinet Mov (N Y) Brief Report BACKGROUND: A defining characteristic of dystonia is its position-dependence. In cervical dystonia (CD), sensory tricks ameliorate head tremor (HT). But it remains unknown whether raising the arms alone has the same impact. METHODS: We analyzed data collected from patients enrolled by the Dystonia Coalition. For 120 patients with HT, we assessed how raising their arms without touching their head changed their HT severity. RESULTS: Forty-eight out of 120 patients exhibited changes in HT severity when raising their arms. These patients were more likely to exhibit decreases in HT severity (N = 35) than increases (N = 13, χ(2) (1, N = 48) = 10.1, p = 0.002). Demographic factors and sensory trick efficacy were not significant predictors of whether HT severity changed when raising their arms. DISCUSSION: Raising the arms without touching the head is a posture that can reduce HT severity in some CD patients. Our results extend the concept of position-dependent motor symptoms in CD to include the position of the arms. HIGHLIGHTS: Head tremor (HT) is a prevalent symptom of cervical dystonia (CD) that can often be disabling. This study demonstrates that raising the arms without touching the head is a posture that can reduce HT severity in some CD patients. Our findings also identify a novel form of position-dependence in CD. Ubiquity Press 2021-06-23 /pmc/articles/PMC8231450/ /pubmed/34221696 http://dx.doi.org/10.5334/tohm.623 Text en Copyright: © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
spellingShingle Brief Report
Cisneros, Elizabeth
Vu, Jeanne P.
Lee, Ha Yeon
Chen, Qiyu
Benadof, Casey N.
Zhang, Zheng
Pettitt, Emily A.
Joshi, Subhagya K.
Barbano, Richard L.
Jankovic, Joseph
Jinnah, Hyder A.
Perlmutter, Joel S.
Berman, Brian D.
Mahajan, Abhimanyu
Goetz, Christopher G.
Stebbins, Glenn T.
Comella, Cynthia L.
Peterson, David A.
Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?
title Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?
title_full Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?
title_fullStr Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?
title_full_unstemmed Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?
title_short Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?
title_sort does raising the arms modify head tremor severity in cervical dystonia?
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231450/
https://www.ncbi.nlm.nih.gov/pubmed/34221696
http://dx.doi.org/10.5334/tohm.623
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