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Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19—The Role of RAGE-RAS Crosstalk

The receptor for advanced glycation-end products (RAGE) is a multiligand receptor with a role in inflammatory and pulmonary pathologies. Hyperactivation of RAGE by its ligands has been reported to sustain inflammation and oxidative stress in common comorbidities of severe COVID-19. RAGE is essential...

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Detalles Bibliográficos
Autores principales: Chiappalupi, Sara, Salvadori, Laura, Donato, Rosario, Riuzzi, Francesca, Sorci, Guglielmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231494/
https://www.ncbi.nlm.nih.gov/pubmed/34204735
http://dx.doi.org/10.3390/biom11060876