Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors

SIMPLE SUMMARY: Anti-angiogenesis agents have shown anti-cancer activity by preventing blood vessel ingrowth, thereby limiting tumour growth and metastasis. Although these molecules lead to prolonged overall survival of cancer patients, therapy resistance is easily acquired. Therefore, novel inhibit...

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Detalles Bibliográficos
Autores principales: Ma, Jin, Ren, Jiang, Thorikay, Midory, van Dinther, Maarten, Sanchez-Duffhues, Gonzalo, Caradec, Josselin, Benderitter, Pascal, Hoflack, Jan, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231556/
https://www.ncbi.nlm.nih.gov/pubmed/34204675
http://dx.doi.org/10.3390/cancers13122951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231556/
https://www.ncbi.nlm.nih.gov/pubmed/34204675
http://dx.doi.org/10.3390/cancers13122951

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