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Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors
SIMPLE SUMMARY: Anti-angiogenesis agents have shown anti-cancer activity by preventing blood vessel ingrowth, thereby limiting tumour growth and metastasis. Although these molecules lead to prolonged overall survival of cancer patients, therapy resistance is easily acquired. Therefore, novel inhibit...
Autores principales: | Ma, Jin, Ren, Jiang, Thorikay, Midory, van Dinther, Maarten, Sanchez-Duffhues, Gonzalo, Caradec, Josselin, Benderitter, Pascal, Hoflack, Jan, ten Dijke, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231556/ https://www.ncbi.nlm.nih.gov/pubmed/34204675 http://dx.doi.org/10.3390/cancers13122951 |
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