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The Hypoxic Microenvironment Induces Stearoyl-CoA Desaturase-1 Overexpression and Lipidomic Profile Changes in Clear Cell Renal Cell Carcinoma

SIMPLE SUMMARY: Clear cell renal cell carcinoma (ccRCC) is characterized by a high rate of cell proliferation and an extensive accumulation of lipids. Uncontrolled cell growth usually generates areas of intratumoral hypoxia that define the tumor phenotype. In this work, we show that, under these mic...

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Detalles Bibliográficos
Autores principales: Melana, Juan Pablo, Mignolli, Francesco, Stoyanoff, Tania, Aguirre, María V., Balboa, María A., Balsinde, Jesús, Rodríguez, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231571/
https://www.ncbi.nlm.nih.gov/pubmed/34199164
http://dx.doi.org/10.3390/cancers13122962