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The Hypoxic Microenvironment Induces Stearoyl-CoA Desaturase-1 Overexpression and Lipidomic Profile Changes in Clear Cell Renal Cell Carcinoma
SIMPLE SUMMARY: Clear cell renal cell carcinoma (ccRCC) is characterized by a high rate of cell proliferation and an extensive accumulation of lipids. Uncontrolled cell growth usually generates areas of intratumoral hypoxia that define the tumor phenotype. In this work, we show that, under these mic...
Autores principales: | Melana, Juan Pablo, Mignolli, Francesco, Stoyanoff, Tania, Aguirre, María V., Balboa, María A., Balsinde, Jesús, Rodríguez, Juan Pablo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231571/ https://www.ncbi.nlm.nih.gov/pubmed/34199164 http://dx.doi.org/10.3390/cancers13122962 |
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