Screening, Diagnostic and Prognostic Tests for COVID-19: A Comprehensive Review

While molecular testing with real-time polymerase chain reaction (RT-PCR) remains the gold-standard test for COVID-19 diagnosis and screening, more rapid or affordable molecular and antigen testing options have been developed. More affordable, point-of-care antigen testing, despite being less sensit...

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Autores principales: Ulinici, Mariana, Covantev, Serghei, Wingfield-Digby, James, Beloukas, Apostolos, Mathioudakis, Alexander G., Corlateanu, Alexandru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231764/
https://www.ncbi.nlm.nih.gov/pubmed/34198591
http://dx.doi.org/10.3390/life11060561
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author Ulinici, Mariana
Covantev, Serghei
Wingfield-Digby, James
Beloukas, Apostolos
Mathioudakis, Alexander G.
Corlateanu, Alexandru
author_facet Ulinici, Mariana
Covantev, Serghei
Wingfield-Digby, James
Beloukas, Apostolos
Mathioudakis, Alexander G.
Corlateanu, Alexandru
author_sort Ulinici, Mariana
collection PubMed
description While molecular testing with real-time polymerase chain reaction (RT-PCR) remains the gold-standard test for COVID-19 diagnosis and screening, more rapid or affordable molecular and antigen testing options have been developed. More affordable, point-of-care antigen testing, despite being less sensitive compared to molecular assays, might be preferable for wider screening initiatives. Simple laboratory, imaging and clinical parameters could facilitate prognostication and triage. This comprehensive review summarises current evidence on the diagnostic, screening and prognostic tests for COVID-19.
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spelling pubmed-82317642021-06-26 Screening, Diagnostic and Prognostic Tests for COVID-19: A Comprehensive Review Ulinici, Mariana Covantev, Serghei Wingfield-Digby, James Beloukas, Apostolos Mathioudakis, Alexander G. Corlateanu, Alexandru Life (Basel) Review While molecular testing with real-time polymerase chain reaction (RT-PCR) remains the gold-standard test for COVID-19 diagnosis and screening, more rapid or affordable molecular and antigen testing options have been developed. More affordable, point-of-care antigen testing, despite being less sensitive compared to molecular assays, might be preferable for wider screening initiatives. Simple laboratory, imaging and clinical parameters could facilitate prognostication and triage. This comprehensive review summarises current evidence on the diagnostic, screening and prognostic tests for COVID-19. MDPI 2021-06-14 /pmc/articles/PMC8231764/ /pubmed/34198591 http://dx.doi.org/10.3390/life11060561 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ulinici, Mariana
Covantev, Serghei
Wingfield-Digby, James
Beloukas, Apostolos
Mathioudakis, Alexander G.
Corlateanu, Alexandru
Screening, Diagnostic and Prognostic Tests for COVID-19: A Comprehensive Review
title Screening, Diagnostic and Prognostic Tests for COVID-19: A Comprehensive Review
title_full Screening, Diagnostic and Prognostic Tests for COVID-19: A Comprehensive Review
title_fullStr Screening, Diagnostic and Prognostic Tests for COVID-19: A Comprehensive Review
title_full_unstemmed Screening, Diagnostic and Prognostic Tests for COVID-19: A Comprehensive Review
title_short Screening, Diagnostic and Prognostic Tests for COVID-19: A Comprehensive Review
title_sort screening, diagnostic and prognostic tests for covid-19: a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231764/
https://www.ncbi.nlm.nih.gov/pubmed/34198591
http://dx.doi.org/10.3390/life11060561
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