Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience

Autism Spectrum Disorder is a neurodevelopmental disorder. Recent data suggest that probiotics can reduce some symptoms of this disorder and Lactobacillus plantarum PS128 has been reported to be especially useful. We recruited a sample of 131 autistic children and adolescents (M:F = 122:19; age: 86....

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Autores principales: Mensi, Martina Maria, Rogantini, Chiara, Marchesi, Michele, Borgatti, Renato, Chiappedi, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231766/
https://www.ncbi.nlm.nih.gov/pubmed/34198499
http://dx.doi.org/10.3390/nu13062036
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author Mensi, Martina Maria
Rogantini, Chiara
Marchesi, Michele
Borgatti, Renato
Chiappedi, Matteo
author_facet Mensi, Martina Maria
Rogantini, Chiara
Marchesi, Michele
Borgatti, Renato
Chiappedi, Matteo
author_sort Mensi, Martina Maria
collection PubMed
description Autism Spectrum Disorder is a neurodevelopmental disorder. Recent data suggest that probiotics can reduce some symptoms of this disorder and Lactobacillus plantarum PS128 has been reported to be especially useful. We recruited a sample of 131 autistic children and adolescents (M:F = 122:19; age: 86.1 ± 41.1 months) and evaluated their changes after use of probiotics by mean of CGI. We found some significant improvements with very few side effects; these positive effects were more evident in younger children. Patients taking Lactobacillus plantarum PS128 had greater improvements and fewer side effects than those taking other probiotics. Our real-life data are consistent with existing literature showing a specific effect of Lactobacillus plantarum PS128 in Autism Spectrum Disorder.
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spelling pubmed-82317662021-06-26 Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience Mensi, Martina Maria Rogantini, Chiara Marchesi, Michele Borgatti, Renato Chiappedi, Matteo Nutrients Communication Autism Spectrum Disorder is a neurodevelopmental disorder. Recent data suggest that probiotics can reduce some symptoms of this disorder and Lactobacillus plantarum PS128 has been reported to be especially useful. We recruited a sample of 131 autistic children and adolescents (M:F = 122:19; age: 86.1 ± 41.1 months) and evaluated their changes after use of probiotics by mean of CGI. We found some significant improvements with very few side effects; these positive effects were more evident in younger children. Patients taking Lactobacillus plantarum PS128 had greater improvements and fewer side effects than those taking other probiotics. Our real-life data are consistent with existing literature showing a specific effect of Lactobacillus plantarum PS128 in Autism Spectrum Disorder. MDPI 2021-06-14 /pmc/articles/PMC8231766/ /pubmed/34198499 http://dx.doi.org/10.3390/nu13062036 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Mensi, Martina Maria
Rogantini, Chiara
Marchesi, Michele
Borgatti, Renato
Chiappedi, Matteo
Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience
title Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience
title_full Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience
title_fullStr Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience
title_full_unstemmed Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience
title_short Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience
title_sort lactobacillus plantarum ps128 and other probiotics in children and adolescents with autism spectrum disorder: a real-world experience
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231766/
https://www.ncbi.nlm.nih.gov/pubmed/34198499
http://dx.doi.org/10.3390/nu13062036
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