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Is SARS-CoV-2 Neutralized More Effectively by IgM and IgA than IgG Having the Same Fab Region?

Recently, recombinant monoclonal antibodies (mAbs) of three Ig isotypes (IgG, IgA, and IgM) sharing the same anti-spike protein Fab region were developed; we evaluated their neutralizing abilities using a pseudo-typed lentivirus coated with the SARS-CoV-2 spike protein and ACE2-transfected Crandell–...

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Detalles Bibliográficos
Autores principales:	Pisil, Yalcin, Yazici, Zafer, Shida, Hisatoshi, Miura, Tomoyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231813/ https://www.ncbi.nlm.nih.gov/pubmed/34199224 http://dx.doi.org/10.3390/pathogens10060751

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