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Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes
Pharmaceutical compounding enables the preparation of unlicensed medicine to meet specific patient needs that do not have a licensed medicine available on the market. It must be performed in the best possible circumstance by certified pharmacists using validated standard operating procedures to obta...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231936/ https://www.ncbi.nlm.nih.gov/pubmed/34199297 http://dx.doi.org/10.3390/pharmaceutics13060875 |
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author | Sebe, István Kovács, István Zelkó, Romána |
author_facet | Sebe, István Kovács, István Zelkó, Romána |
author_sort | Sebe, István |
collection | PubMed |
description | Pharmaceutical compounding enables the preparation of unlicensed medicine to meet specific patient needs that do not have a licensed medicine available on the market. It must be performed in the best possible circumstance by certified pharmacists using validated standard operating procedures to obtain the highest quality medicinal product. The various spinning techniques provide drug delivery systems easily adapted to individual patient’s needs among the emerging technologies. The primary purpose of the present work was to introduce the prototype of a contact drawing device for the compounding of drug delivery systems for individual in-patient needs. The preliminary experiments resulted in oriented fibers of micrometer diameter range. The device can be placed in controlled conditions and could provide drug-loaded fibrous sheets for further treatments assuring the individual patient’s medicine need of the required quality. |
format | Online Article Text |
id | pubmed-8231936 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82319362021-06-26 Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes Sebe, István Kovács, István Zelkó, Romána Pharmaceutics Article Pharmaceutical compounding enables the preparation of unlicensed medicine to meet specific patient needs that do not have a licensed medicine available on the market. It must be performed in the best possible circumstance by certified pharmacists using validated standard operating procedures to obtain the highest quality medicinal product. The various spinning techniques provide drug delivery systems easily adapted to individual patient’s needs among the emerging technologies. The primary purpose of the present work was to introduce the prototype of a contact drawing device for the compounding of drug delivery systems for individual in-patient needs. The preliminary experiments resulted in oriented fibers of micrometer diameter range. The device can be placed in controlled conditions and could provide drug-loaded fibrous sheets for further treatments assuring the individual patient’s medicine need of the required quality. MDPI 2021-06-13 /pmc/articles/PMC8231936/ /pubmed/34199297 http://dx.doi.org/10.3390/pharmaceutics13060875 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sebe, István Kovács, István Zelkó, Romána Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes |
title | Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes |
title_full | Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes |
title_fullStr | Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes |
title_full_unstemmed | Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes |
title_short | Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes |
title_sort | design of the prototype of contact drawing device for potential individual therapeutic fiber formation purposes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231936/ https://www.ncbi.nlm.nih.gov/pubmed/34199297 http://dx.doi.org/10.3390/pharmaceutics13060875 |
work_keys_str_mv | AT sebeistvan designoftheprototypeofcontactdrawingdeviceforpotentialindividualtherapeuticfiberformationpurposes AT kovacsistvan designoftheprototypeofcontactdrawingdeviceforpotentialindividualtherapeuticfiberformationpurposes AT zelkoromana designoftheprototypeofcontactdrawingdeviceforpotentialindividualtherapeuticfiberformationpurposes |