Cargando…

Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes

Pharmaceutical compounding enables the preparation of unlicensed medicine to meet specific patient needs that do not have a licensed medicine available on the market. It must be performed in the best possible circumstance by certified pharmacists using validated standard operating procedures to obta...

Descripción completa

Detalles Bibliográficos
Autores principales: Sebe, István, Kovács, István, Zelkó, Romána
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231936/
https://www.ncbi.nlm.nih.gov/pubmed/34199297
http://dx.doi.org/10.3390/pharmaceutics13060875
_version_ 1783713529956663296
author Sebe, István
Kovács, István
Zelkó, Romána
author_facet Sebe, István
Kovács, István
Zelkó, Romána
author_sort Sebe, István
collection PubMed
description Pharmaceutical compounding enables the preparation of unlicensed medicine to meet specific patient needs that do not have a licensed medicine available on the market. It must be performed in the best possible circumstance by certified pharmacists using validated standard operating procedures to obtain the highest quality medicinal product. The various spinning techniques provide drug delivery systems easily adapted to individual patient’s needs among the emerging technologies. The primary purpose of the present work was to introduce the prototype of a contact drawing device for the compounding of drug delivery systems for individual in-patient needs. The preliminary experiments resulted in oriented fibers of micrometer diameter range. The device can be placed in controlled conditions and could provide drug-loaded fibrous sheets for further treatments assuring the individual patient’s medicine need of the required quality.
format Online
Article
Text
id pubmed-8231936
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-82319362021-06-26 Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes Sebe, István Kovács, István Zelkó, Romána Pharmaceutics Article Pharmaceutical compounding enables the preparation of unlicensed medicine to meet specific patient needs that do not have a licensed medicine available on the market. It must be performed in the best possible circumstance by certified pharmacists using validated standard operating procedures to obtain the highest quality medicinal product. The various spinning techniques provide drug delivery systems easily adapted to individual patient’s needs among the emerging technologies. The primary purpose of the present work was to introduce the prototype of a contact drawing device for the compounding of drug delivery systems for individual in-patient needs. The preliminary experiments resulted in oriented fibers of micrometer diameter range. The device can be placed in controlled conditions and could provide drug-loaded fibrous sheets for further treatments assuring the individual patient’s medicine need of the required quality. MDPI 2021-06-13 /pmc/articles/PMC8231936/ /pubmed/34199297 http://dx.doi.org/10.3390/pharmaceutics13060875 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sebe, István
Kovács, István
Zelkó, Romána
Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes
title Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes
title_full Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes
title_fullStr Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes
title_full_unstemmed Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes
title_short Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes
title_sort design of the prototype of contact drawing device for potential individual therapeutic fiber formation purposes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231936/
https://www.ncbi.nlm.nih.gov/pubmed/34199297
http://dx.doi.org/10.3390/pharmaceutics13060875
work_keys_str_mv AT sebeistvan designoftheprototypeofcontactdrawingdeviceforpotentialindividualtherapeuticfiberformationpurposes
AT kovacsistvan designoftheprototypeofcontactdrawingdeviceforpotentialindividualtherapeuticfiberformationpurposes
AT zelkoromana designoftheprototypeofcontactdrawingdeviceforpotentialindividualtherapeuticfiberformationpurposes