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Differential Effects of Furin Deficiency on Insulin Receptor Processing and Glucose Control in Liver and Pancreatic β Cells of Mice

The insulin receptor (IR) is critically involved in maintaining glucose homeostasis. It undergoes proteolytic cleavage by proprotein convertases, which is an essential step for its activation. The importance of the insulin receptor in liver is well established, but its role in pancreatic β cells is...

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Detalles Bibliográficos
Autores principales:	Coppola, Ilaria, Brouwers, Bas, Meulemans, Sandra, Ramos-Molina, Bruno, Creemers, John W. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231939/ https://www.ncbi.nlm.nih.gov/pubmed/34198511 http://dx.doi.org/10.3390/ijms22126344

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