Cargando…
Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH
Empagliflozin, an established treatment for type 2 diabetes (T2DM), has shown beneficial effects on liver steatosis and fibrosis in animals and in humans with T2DM, non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH). However, little is known about the effects of empagliflozin on li...
Autores principales: | Perakakis, Nikolaos, Chrysafi, Pavlina, Feigh, Michael, Veidal, Sanne Skovgard, Mantzoros, Christos S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232001/ https://www.ncbi.nlm.nih.gov/pubmed/34199317 http://dx.doi.org/10.3390/ijms22126332 |
Ejemplares similares
-
Both Elafibranor and Liraglutide Improve NAFLD / NASH but Affect Differentially the Hepatic Lipidome and Metabolome in a Diet-Induced Obese and Biopsy-Confirmed Mouse Model of NASH
por: Perakakis, Nikolaos, et al.
Publicado: (2021) -
The Selective Peroxisome Proliferator‐Activated Receptor Gamma Modulator CHS‐131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis
por: Perakakis, Nikolaos, et al.
Publicado: (2020) -
Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH
por: Baandrup Kristiansen, Maria Nicoline, et al.
Publicado: (2019) -
Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet‐induced obese and biopsy‐confirmed mouse model of NASH
por: Møllerhøj, Mathias B., et al.
Publicado: (2022) -
Leptin alters energy intake and fat mass but not energy expenditure in lean subjects
por: Chrysafi, Pavlina, et al.
Publicado: (2020)