Cargando…
Emerging Roles of Small GTPases in Islet β-Cell Function
Several small guanosine triphosphatases (GTPases) from the Ras protein superfamily regulate glucose-stimulated insulin secretion in the pancreatic islet β-cell. The Rho family GTPases Cdc42 and Rac1 are primarily involved in relaying key signals in several cellular functions, including vesicle traff...
Autores principales: | Veluthakal, Rajakrishnan, Thurmond, Debbie C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232272/ https://www.ncbi.nlm.nih.gov/pubmed/34203728 http://dx.doi.org/10.3390/cells10061503 |
Ejemplares similares
-
Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee β-cell Function and Protection
por: Chatterjee Bhowmick, Diti, et al.
Publicado: (2021) -
Toward Ameliorating Insulin Resistance: Targeting a Novel PAK1 Signaling Pathway Required for Skeletal Muscle Mitochondrial Function
por: Balakrishnan, Rekha, et al.
Publicado: (2023) -
Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells
por: Kalwat, Michael A, et al.
Publicado: (2013) -
PAK1 limits the expression of the pro-apoptotic protein Bad in pancreatic islet β-cells
por: Wang, Zhanxiang, et al.
Publicado: (2012) -
Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass
por: Oh, Eunjin, et al.
Publicado: (2018)