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Targeting HSF1 as a Therapeutic Strategy for Multiple Mechanisms of EGFR Inhibitor Resistance in EGFR Mutant Non-Small-Cell Lung Cancer

SIMPLE SUMMARY: We attempted to identify target proteins and compounds that can be used to overcome EGFR-TKI resistance in NSCLC. To accomplish this, we generated EGFR inhibitor erlotinib-resistant HCC827-ErlR cells and obtained a list of differentially expressed genes. Then, we performed connectivi...

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Detalles Bibliográficos
Autores principales:	Lee, Sangah, Jung, Jiyae, Lee, Yu-Jin, Kim, Seon-Kyu, Kim, Jung-Ae, Kim, Bo-Kyung, Park, Kyung Chan, Kwon, Byoung-Mog, Han, Dong Cho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232331/ https://www.ncbi.nlm.nih.gov/pubmed/34203709 http://dx.doi.org/10.3390/cancers13122987

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