Cargando…

Increased Tumor Growth Rate and Mesenchymal Properties of NSCLC-Patient-Derived Xenograft Models during Serial Transplantation

SIMPLE SUMMARY: Advances have been made in the study of NSCLC tumors using in vivo models, such as patient-derived xenografts (PDXs). However, the number of PDX models that can represent the heterogeneity of NSCLC between different individuals is still limited. We successfully established nine PDX m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pardo-Sánchez, José Miguel, Mancheño, Nuria, Cerón, José, Jordá, Carlos, Ansotegui, Emilio, Juan, Óscar, Palanca, Sarai, Cremades, Antonio, Gandía, Carolina, Farràs, Rosa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232339/ https://www.ncbi.nlm.nih.gov/pubmed/34198671 http://dx.doi.org/10.3390/cancers13122980

Ejemplares similares

Correction: Pardo-Sánchez et al. Increased Tumor Growth Rate and Mesenchymal Properties of NSCLC-Patient-Derived Xenograft Models during Serial Transplantation. Cancers 2021, 13, 2980
por: Pardo-Sánchez, José Miguel, et al.
Publicado: (2021)

Technical Validation and Clinical Implications of Ultrasensitive PCR Approaches for EGFR-Thr790Met Mutation Detection in Pretreatment FFPE Samples and in Liquid Biopsies from Non-Small Cell Lung Cancer Patients
por: Simarro, Javier, et al.
Publicado: (2022)

Impact of Molecular Testing Using Next-Generation Sequencing in the Clinical Management of Patients with Non-Small Cell Lung Cancer in a Public Healthcare Hospital
por: Simarro, Javier, et al.
Publicado: (2023)

Development, Implementation and Assessment of Molecular Diagnostics by Next Generation Sequencing in Personalized Treatment of Cancer: Experience of a Public Reference Healthcare Hospital
por: Simarro, Javier, et al.
Publicado: (2019)

Utility of Next-Generation Sequencing in the Reconstruction of Clonal Architecture in a Patient with an EGFR Mutated Advanced Non-Small Cell Lung Cancer: A Case Report
por: Simarro, Javier, et al.
Publicado: (2022)

Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity
por: Martínez-Férriz, Arantxa, et al.
Publicado: (2023)

Serial cytogenetic studies of human colonic tumour xenografts.
por: Reeves, B. R., et al.
Publicado: (1978)

Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation
por: Wegner, Catherine S., et al.
Publicado: (2018)

Phenotypic stability and metastatic behaviour of serially xenografted rat mesotheliomas.
por: Edwards, R. E., et al.
Publicado: (1990)

Comprehensive serial biobanking in advanced NSCLC: feasibility, challenges and perspectives
por: Wessels, Sabine, et al.
Publicado: (2020)

Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts
por: Vlahovic, G, et al.
Publicado: (2007)

Human tumour xenografts established and serially transplanted in mice immunologically deprived by thymectomy, cytosine arabinoside and whole-body irradiation.
por: Selby, P. J., et al.
Publicado: (1980)

Bevacizumab counteracts VEGF-dependent resistance to erlotinib in an EGFR-mutated NSCLC xenograft model
por: Masuda, Chinami, et al.
Publicado: (2017)

New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2
por: Pérez-Benavente, Beatriz, et al.
Publicado: (2022)

Use of self-organizing maps for analyzing the behavior of canines displaced towards midline under interceptive treatment
por: Gandía-Aguiló, Vicente, et al.
Publicado: (2017)

The Role of Serial Liquid Biopsy in the Management of Metastatic Non-Small Cell Lung Cancer (NSCLC)
por: Sama, Srikar, et al.
Publicado: (2022)

Improvement of Radiation-Mediated Immunosuppression of Human NSCLC Tumour Xenografts in a Nude Rat Model
por: Tokalov, Sergey V., et al.
Publicado: (2010)

DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts
por: Nguyen, Long V., et al.
Publicado: (2014)

A Fermented Wheat Germ Extract Contains Protein Components Active against NSCLC Xenografts In Vivo
por: Levis, Daniel J., et al.
Publicado: (2023)

Antitumor Activity and Pharmacokinetics of a Morpholino‐anthracycline Derivative (KRN8602) against Human Breast Carcinoma Xenografts Serially Transplanted into Nude Mice
por: Kubota, Tetsuro, et al.
Publicado: (1990)

High levels of chromosomal aberrations negatively associate with benefit to checkpoint inhibition in NSCLC
por: Frigola, Joan, et al.
Publicado: (2022)

In Vitro Effect of Δ9-Tetrahydrocannabinol and Cannabidiol on Cancer-Associated Fibroblasts Isolated from Lung Cancer
por: Milián, Lara, et al.
Publicado: (2022)

Serial patient-derived orthotopic xenografting of adenoid cystic carcinomas recapitulates stable expression of phenotypic alterations and innervation
por: Cornett, Ashley, et al.
Publicado: (2019)

Serial Expression Analysis: a web tool for the analysis of serial gene expression data
por: Nueda, Maria José, et al.
Publicado: (2010)

Correlation of serum electrolytes with serial miRNA in advanced stage non-small cell lung cancer (NSCLC) in Indonesia
por: Hanafi, Arif Riswahyudi, et al.
Publicado: (2021)

Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH
por: Swiatnicki, Matthew R., et al.
Publicado: (2022)

Lung tumorspheres reveal cancer stem cell-like properties and a score with prognostic impact in resected non-small-cell lung cancer
por: Herreros-Pomares, Alejandro, et al.
Publicado: (2019)

Noninvasive Bioluminescence Imaging of AKT Kinase Activity in Subcutaneous and Orthotopic NSCLC Xenografts: Correlation of AKT Activity with Tumor Growth Kinetics()
por: Suchowski, Karina, et al.
Publicado: (2017)

Telomerase deficiency and dysfunctional telomeres in the lung tumor microenvironment impair tumor progression in NSCLC mouse models and patient-derived xenografts
por: Piñeiro-Hermida, Sergio, et al.
Publicado: (2023)

Treating KRAS-mutant NSCLC: latest evidence and clinical consequences
por: Garrido, Pilar, et al.
Publicado: (2017)

Transtinib, a potent tyrosine kinase inhibitor inhibits L858R/T790M mutant NSCLC cell lines and xenografts
por: Hu, Peng, et al.
Publicado: (2016)

DFIQ, a Novel Quinoline Derivative, Shows Anticancer Potential by Inducing Apoptosis and Autophagy in NSCLC Cell and In Vivo Zebrafish Xenograft Models
por: Huang, Hurng-Wern, et al.
Publicado: (2020)

Human mesenchymal stromal cells inhibit tumor growth in orthotopic glioblastoma xenografts
por: Pacioni, Simone, et al.
Publicado: (2017)

Regulation of GSK3β-FBXW7-JUNB Axis
por: Pérez-Benavente, Beatriz, et al.
Publicado: (2013)

The Role of Serial Imaging in Neurocysticercosis for Disease Resolution
por: Gonzalez, Sheyla, et al.
Publicado: (2021)

Cancer therapy and cardiotoxicity: The need of serial Doppler echocardiography
por: Galderisi, Maurizio, et al.
Publicado: (2007)

MALDI mass spectrometry imaging of erlotinib administered in combination with bevacizumab in xenograft mice bearing B901L, EGFR-mutated NSCLC cells
por: Nishidate, Masanobu, et al.
Publicado: (2017)

Histology and ultrastructure of serially transplanted rat mesotheliomas.
por: Wagner, J. C., et al.
Publicado: (1982)

‘Biaxial serial excision’ or ‘polyaxial serial excision’
por: Alexander, G., et al.
Publicado: (2013)

Rescuing mesenchymal stem cell regenerative properties on hydrogel substrates post serial expansion
por: Rao, Varsha V., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_r0gee9ugkgovfbeku0quu5tttj