Derivatives of Natural Chlorophylls as Agents for Antimicrobial Photodynamic Therapy

The rapid growth of drug-resistant bacteria all over the world has given rise to a major research challenge, namely a search for alternative treatments to which bacteria will be unable to develop resistance. Photodynamic therapy is an approach of this kind. It involves the use of photosensitizers in...

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Autores principales: Suvorov, Nikita, Pogorilyy, Viktor, Diachkova, Ekaterina, Vasil’ev, Yuri, Mironov, Andrey, Grin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232654/
https://www.ncbi.nlm.nih.gov/pubmed/34203767
http://dx.doi.org/10.3390/ijms22126392
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author Suvorov, Nikita
Pogorilyy, Viktor
Diachkova, Ekaterina
Vasil’ev, Yuri
Mironov, Andrey
Grin, Mikhail
author_facet Suvorov, Nikita
Pogorilyy, Viktor
Diachkova, Ekaterina
Vasil’ev, Yuri
Mironov, Andrey
Grin, Mikhail
author_sort Suvorov, Nikita
collection PubMed
description The rapid growth of drug-resistant bacteria all over the world has given rise to a major research challenge, namely a search for alternative treatments to which bacteria will be unable to develop resistance. Photodynamic therapy is an approach of this kind. It involves the use of photosensitizers in combination with visible light at a certain wavelength to excite the former and generate reactive oxygen species. Various synthetic heterocyclic compounds are used as photosensitizers. Of these, derivatives of natural chlorophylls have a special place due to their properties. This review deals with the use of such compounds in antimicrobial PDT.
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spelling pubmed-82326542021-06-26 Derivatives of Natural Chlorophylls as Agents for Antimicrobial Photodynamic Therapy Suvorov, Nikita Pogorilyy, Viktor Diachkova, Ekaterina Vasil’ev, Yuri Mironov, Andrey Grin, Mikhail Int J Mol Sci Review The rapid growth of drug-resistant bacteria all over the world has given rise to a major research challenge, namely a search for alternative treatments to which bacteria will be unable to develop resistance. Photodynamic therapy is an approach of this kind. It involves the use of photosensitizers in combination with visible light at a certain wavelength to excite the former and generate reactive oxygen species. Various synthetic heterocyclic compounds are used as photosensitizers. Of these, derivatives of natural chlorophylls have a special place due to their properties. This review deals with the use of such compounds in antimicrobial PDT. MDPI 2021-06-15 /pmc/articles/PMC8232654/ /pubmed/34203767 http://dx.doi.org/10.3390/ijms22126392 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Suvorov, Nikita
Pogorilyy, Viktor
Diachkova, Ekaterina
Vasil’ev, Yuri
Mironov, Andrey
Grin, Mikhail
Derivatives of Natural Chlorophylls as Agents for Antimicrobial Photodynamic Therapy
title Derivatives of Natural Chlorophylls as Agents for Antimicrobial Photodynamic Therapy
title_full Derivatives of Natural Chlorophylls as Agents for Antimicrobial Photodynamic Therapy
title_fullStr Derivatives of Natural Chlorophylls as Agents for Antimicrobial Photodynamic Therapy
title_full_unstemmed Derivatives of Natural Chlorophylls as Agents for Antimicrobial Photodynamic Therapy
title_short Derivatives of Natural Chlorophylls as Agents for Antimicrobial Photodynamic Therapy
title_sort derivatives of natural chlorophylls as agents for antimicrobial photodynamic therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232654/
https://www.ncbi.nlm.nih.gov/pubmed/34203767
http://dx.doi.org/10.3390/ijms22126392
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