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Analysis of NHEJ-Based DNA Repair after CRISPR-Mediated DNA Cleavage

Genome editing using CRISPR-Cas9 nucleases is based on the repair of the DNA double-strand break (DSB). In eukaryotic cells, DSBs are rejoined through homology-directed repair (HDR), non-homologous end joining (NHEJ) or microhomology-mediated end joining (MMEJ) pathways. Among these, it is thought t...

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Detalles Bibliográficos
Autores principales:	Song, Beomjong, Yang, Soyeon, Hwang, Gue-Ho, Yu, Jihyeon, Bae, Sangsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232687/ https://www.ncbi.nlm.nih.gov/pubmed/34203807 http://dx.doi.org/10.3390/ijms22126397

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