Cargando…
The PD-L1/PD-1 Axis Blocks Neutrophil Cytotoxicity in Cancer
The PD-L1/PD-1 axis mediates immune tolerance and promotes tumor growth and progression via the inhibition of anti-tumor immunity. Blocking the interaction between PD-L1 and PD-1 was clinically shown to be beneficial in maintaining the anti-tumor functions of the adaptive immune system. Still, the c...
Autores principales: | Yajuk, Olga, Baron, Maya, Toker, Sapir, Zelter, Tamir, Fainsod-Levi, Tanya, Granot, Zvi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232689/ https://www.ncbi.nlm.nih.gov/pubmed/34203915 http://dx.doi.org/10.3390/cells10061510 |
Ejemplares similares
-
Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria
por: Zelter, Tamir, et al.
Publicado: (2022) -
ICAM-1 on Breast Cancer Cells Suppresses Lung Metastasis but Is Dispensable for Tumor Growth and Killing by Cytotoxic T Cells
por: Regev, Ofer, et al.
Publicado: (2022) -
Rational development of molecularly imprinted nanoparticles for blocking PD-1/PD-L1 axis
por: Gu, Zikuan, et al.
Publicado: (2022) -
Blocking the PD-1/PD-L1 axis enhanced cisplatin chemotherapy in osteosarcoma in vitro and in vivo
por: Liu, Xiaoqiang, et al.
Publicado: (2019) -
Tumor-associated neutrophils suppress antitumor immunity of NK cells through the PD-L1/PD-1 axis
por: Sun, Rui, et al.
Publicado: (2020)