Investigation of the Anti-Methicillin-Resistant Staphylococcus aureus Activity of (+)-Tanikolide- and (+)-Malyngolide-Based Analogues Prepared by Asymmetric Synthesis

Herein, we report antibacterial and antifungal evaluation of a series of previously prepared (+)-tanikolide analogues. One analogue, (4S,6S)-4-methyltanikolide, displayed promising anti-methicillin-resistant Staphylococcus aureus activity with a MIC of 12.5 µg/mL. Based on the antimicrobial properti...

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Detalles Bibliográficos
Autores principales: Breheny, Joseph, Kingston, Cian, Doran, Robert, Anes, Joao, Martins, Marta, Fanning, Séamus, Guiry, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232695/
https://www.ncbi.nlm.nih.gov/pubmed/34203787
http://dx.doi.org/10.3390/ijms22126400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232695/
https://www.ncbi.nlm.nih.gov/pubmed/34203787
http://dx.doi.org/10.3390/ijms22126400

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