Cargando…

Identification of Circulating Gene Expression Signatures of Intracranial Aneurysm in Peripheral Blood Mononuclear Cells

Peripheral blood mononuclear cells (PBMCs) play an important role in the inflammation that accompanies intracranial aneurysm (IA) pathophysiology. We hypothesized that PBMCs have different transcriptional profiles in patients harboring IAs as compared to IA-free controls, which could be the basis fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tutino, Vincent M., Zebraski, Haley R., Rajabzadeh-Oghaz, Hamidreza, Waqas, Muhammad, Jarvis, James N., Bach, Konrad, Mokin, Maxim, Snyder, Kenneth V., Siddiqui, Adnan H., Poppenberg, Kerry E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232768/ https://www.ncbi.nlm.nih.gov/pubmed/34203780 http://dx.doi.org/10.3390/diagnostics11061092

Ejemplares similares

Aberrant Whole Blood Gene Expression in the Lumen of Human Intracranial Aneurysms
por: Tutino, Vincent M., et al.
Publicado: (2021)

Epigenetic landscapes of intracranial aneurysm risk haplotypes implicate enhancer function of endothelial cells and fibroblasts in dysregulated gene expression
por: Poppenberg, Kerry E., et al.
Publicado: (2021)

Aneurysm risk metrics and hemodynamics are associated with greater vessel wall enhancement in intracranial aneurysms
por: Veeturi, Sricharan S., et al.
Publicado: (2021)

RNA Expression Signatures of Intracranial Aneurysm Growth Trajectory Identified in Circulating Whole Blood
por: Poppenberg, Kerry E., et al.
Publicado: (2023)

Circulating neutrophil transcriptome may reveal intracranial aneurysm signature
por: Tutino, Vincent M., et al.
Publicado: (2018)

An Image-Based Workflow for Objective Vessel Wall Enhancement Quantification in Intracranial Aneurysms
por: Veeturi, Sricharan S., et al.
Publicado: (2021)

Classification models using circulating neutrophil transcripts can detect unruptured intracranial aneurysm
por: Poppenberg, Kerry E., et al.
Publicado: (2020)

Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms
por: Tutino, Vincent M., et al.
Publicado: (2018)

Identification of intima-to-media signals for flow-induced vascular remodeling using correlative gene expression analysis
por: Kolega, John, et al.
Publicado: (2021)

Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium
por: Poppenberg, Kerry E., et al.
Publicado: (2019)

Whole blood transcriptome biomarkers of unruptured intracranial aneurysm
por: Poppenberg, Kerry E., et al.
Publicado: (2020)

Hemodynamic Analysis Shows High Wall Shear Stress Is Associated with Intraoperatively Observed Thin Wall Regions of Intracranial Aneurysms
por: Veeturi, Sricharan S., et al.
Publicado: (2022)

Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes
por: Poppenberg, Kerry E., et al.
Publicado: (2021)

Techniques in distal access of wide-necked giant intracranial aneurysms during treatment with flow diversion
por: Kan, Peter, et al.
Publicado: (2015)

Analysis of chromatin data supports a role for CD14+ monocytes/macrophages in mediating genetic risk for juvenile idiopathic arthritis
por: Crinzi, Elizabeth A., et al.
Publicado: (2022)

Improving accuracy for finite element modeling of endovascular coiling of intracranial aneurysm
por: Damiano, Robert J., et al.
Publicado: (2019)

Use of patient specific 3D printed neurovascular phantoms to simulate mechanical thrombectomy
por: Sommer, Kelsey N., et al.
Publicado: (2021)

Isolation of RNA from Acute Ischemic Stroke Clots Retrieved by Mechanical Thrombectomy
por: Tutino, Vincent M., et al.
Publicado: (2021)

Ruptured mycotic cerebral aneurysm development from pseudoocclusion due to septic embolism
por: Sorkin, Grant C., et al.
Publicado: (2013)

The feasibility of developing biomarkers from peripheral blood mononuclear cell RNAseq data in children with juvenile idiopathic arthritis using machine learning approaches
por: Poppenberg, Kerry E., et al.
Publicado: (2019)

Revascularization Outcome Prediction for A Direct Aspiration-First Pass Technique (ADAPT) from Pre-Treatment Imaging and Machine Learning
por: Patel, Tatsat R., et al.
Publicado: (2021)

The Use of Flow Diversion for the Treatment of Intracranial Aneurysms: Expansion of Indications
por: Brouillard, Adam M, et al.
Publicado: (2016)

Circulating microRNAs in patients with intracranial aneurysms
por: Meeuwsen, John A. L., et al.
Publicado: (2017)

Endovascular treatment of unruptured posterior circulation intracranial aneurysms
por: Lv, Xianli, et al.
Publicado: (2016)

Prospective study on embolization of intracranial aneurysms with the pipeline device: the PREMIER study 1 year results
por: Hanel, Ricardo A, et al.
Publicado: (2020)

Endothelial Nitric Oxide Synthase and Superoxide Mediate Hemodynamic Initiation of Intracranial Aneurysms
por: Liaw, Nicholas, et al.
Publicado: (2014)

A Critical Role for Proinflammatory Behavior of Smooth Muscle Cells in Hemodynamic Initiation of Intracranial Aneurysm
por: Mandelbaum, Max, et al.
Publicado: (2013)

Circulating microRNAs Serve as Novel Biological Markers for Intracranial Aneurysms
por: Li, Pengxiang, et al.
Publicado: (2014)

Circulating proteomic panels for risk stratification of intracranial aneurysm and its rupture
por: Xiong, Yueting, et al.
Publicado: (2022)

Treatment of ruptured intracranial aneurysms yesterday and now
por: Hammer, Alexander, et al.
Publicado: (2017)

Extracranial-intracranial bypass surgery for intracranial aneurysm of the anterior cerebral circulation: A systematic review and meta-analysis
por: Chen, Yang, et al.
Publicado: (2023)

Mycotic aneurysms of the intracranial and peripheral circulation: A rare complication of bacterial endocarditis
por: Jain, Rajendra Singh, et al.
Publicado: (2014)

Clipping versus coiling in posterior circulation intracranial aneurysms: a meta-analysis
por: Tsianaka, Eleni, et al.
Publicado: (2019)

Risk Factors for Higher Volume of Hemorrhage in Ruptured Anterior Circulation Intracranial Aneurysms
por: Ya, Xiaolong, et al.
Publicado: (2020)

Ruptured intracranial aneurysm presenting as cerebral circulation insufficiency: A case report
por: Zhao, Long, et al.
Publicado: (2021)

Multiple Anterior and Posterior Circulation Intracranial Fenestrations presenting With Aneurysmal Subarachnoid Hemorrhage
por: Scranton, Robert A, et al.
Publicado: (2021)

Risk Factors of Anterior Circulation Intracranial Aneurysm Rupture: Extracranial Carotid Artery Tortuosity and Aneurysm Morphologic Parameters
por: Pei, Yusong, et al.
Publicado: (2021)

Ruptured Intracranial Aneurysms
por: McCaughey, W. T. E.
Publicado: (1956)

An overview of intracranial aneurysms
por: Keedy, Alexander
Publicado: (2006)

Intracranial Arterial Aneurysms
por: Brody, Bernard S.
Publicado: (1944)

Cannot write session to /tmp/vufind_sessions/sess_96fa6pn7ghnvm202m5vqq8of4j