Cargando…
A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces
Recent investigations on the anti-adhesive properties of polysulfobetaine methacrylate (pSBMA) coatings had shown promising potential as antifouling surfaces and have given the impetus for the present paper, where a pSBMA coating is applied via photopolymerization on a macro-roughened, sandblasted,...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232804/ https://www.ncbi.nlm.nih.gov/pubmed/34203760 http://dx.doi.org/10.3390/ma14123303 |
_version_ | 1783713716605288448 |
---|---|
author | Gülses, Aydin Lopar, Antonia Es-Souni, Martha Emmert, Marie Es-Souni, Mona Behrens, Eleonore Naujokat, Hendrik Liedtke, Kim Rouven Acil, Yahya Wiltfang, Jörg Flörke, Christian |
author_facet | Gülses, Aydin Lopar, Antonia Es-Souni, Martha Emmert, Marie Es-Souni, Mona Behrens, Eleonore Naujokat, Hendrik Liedtke, Kim Rouven Acil, Yahya Wiltfang, Jörg Flörke, Christian |
author_sort | Gülses, Aydin |
collection | PubMed |
description | Recent investigations on the anti-adhesive properties of polysulfobetaine methacrylate (pSBMA) coatings had shown promising potential as antifouling surfaces and have given the impetus for the present paper, where a pSBMA coating is applied via photopolymerization on a macro-roughened, sandblasted, and acid-etched titanium implant surface in order to assess its antifouling properties. Current emphasis is placed on how the coating is efficient against the adhesion of Enterococcus faecalis by quantitative assessment of colony forming units and qualitative investigation of fluorescence imaging and scanning electron microscopy. pSBMA coatings via photopolymerization of titanium surfaces seems to be a promising antiadhesion strategy, which should bring substantial benefits once certain aspects such as biodegradation and osseointegration were addressed. Additionally, commercial SAL-titanium substrates may be coated with the super-hydrophilic coating, appearing resistant to physiological salt concentrations and most importantly lowering E. faecalis colonization significantly, compared to titanium substrates in the as-received state. It is very likely that pSBMA coatings may also prevent the adhesion of other germs. |
format | Online Article Text |
id | pubmed-8232804 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82328042021-06-26 A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces Gülses, Aydin Lopar, Antonia Es-Souni, Martha Emmert, Marie Es-Souni, Mona Behrens, Eleonore Naujokat, Hendrik Liedtke, Kim Rouven Acil, Yahya Wiltfang, Jörg Flörke, Christian Materials (Basel) Article Recent investigations on the anti-adhesive properties of polysulfobetaine methacrylate (pSBMA) coatings had shown promising potential as antifouling surfaces and have given the impetus for the present paper, where a pSBMA coating is applied via photopolymerization on a macro-roughened, sandblasted, and acid-etched titanium implant surface in order to assess its antifouling properties. Current emphasis is placed on how the coating is efficient against the adhesion of Enterococcus faecalis by quantitative assessment of colony forming units and qualitative investigation of fluorescence imaging and scanning electron microscopy. pSBMA coatings via photopolymerization of titanium surfaces seems to be a promising antiadhesion strategy, which should bring substantial benefits once certain aspects such as biodegradation and osseointegration were addressed. Additionally, commercial SAL-titanium substrates may be coated with the super-hydrophilic coating, appearing resistant to physiological salt concentrations and most importantly lowering E. faecalis colonization significantly, compared to titanium substrates in the as-received state. It is very likely that pSBMA coatings may also prevent the adhesion of other germs. MDPI 2021-06-15 /pmc/articles/PMC8232804/ /pubmed/34203760 http://dx.doi.org/10.3390/ma14123303 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Gülses, Aydin Lopar, Antonia Es-Souni, Martha Emmert, Marie Es-Souni, Mona Behrens, Eleonore Naujokat, Hendrik Liedtke, Kim Rouven Acil, Yahya Wiltfang, Jörg Flörke, Christian A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
title | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
title_full | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
title_fullStr | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
title_full_unstemmed | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
title_short | A Novel Surface Modification Strategy via Photopolymerized Poly-Sulfobetaine Methacrylate Coating to Prevent Bacterial Adhesion on Titanium Surfaces |
title_sort | novel surface modification strategy via photopolymerized poly-sulfobetaine methacrylate coating to prevent bacterial adhesion on titanium surfaces |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232804/ https://www.ncbi.nlm.nih.gov/pubmed/34203760 http://dx.doi.org/10.3390/ma14123303 |
work_keys_str_mv | AT gulsesaydin anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT loparantonia anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT essounimartha anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT emmertmarie anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT essounimona anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT behrenseleonore anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT naujokathendrik anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT liedtkekimrouven anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT acilyahya anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT wiltfangjorg anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT florkechristian anovelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT gulsesaydin novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT loparantonia novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT essounimartha novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT emmertmarie novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT essounimona novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT behrenseleonore novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT naujokathendrik novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT liedtkekimrouven novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT acilyahya novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT wiltfangjorg novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces AT florkechristian novelsurfacemodificationstrategyviaphotopolymerizedpolysulfobetainemethacrylatecoatingtopreventbacterialadhesionontitaniumsurfaces |