Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans

Protein aggregation causes intracellular changes in neurons, which elicit signals to modulate proteostasis in the periphery. Beyond the nervous system, a fundamental question is whether other organs also communicate their proteostasis status to distal tissues. Here, we examine whether proteostasis o...

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Detalles Bibliográficos
Autores principales: Calculli, Giuseppe, Lee, Hyun Ju, Shen, Koning, Pham, Uyen, Herholz, Marija, Trifunovic, Aleksandra, Dillin, Andrew, Vilchez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232903/
https://www.ncbi.nlm.nih.gov/pubmed/34172445
http://dx.doi.org/10.1126/sciadv.abg3012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232903/
https://www.ncbi.nlm.nih.gov/pubmed/34172445
http://dx.doi.org/10.1126/sciadv.abg3012

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