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Effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals

Stress is a contributing factor to painful temporomandibular disorders (TMD). Nevertheless, the underpinnings of this relationship are not fully understood. OBJECTIVE: To investigate the effects of acute mental stress on conditioned pain modulation (CPM) in TMD patients compared with healthy individ...

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Autores principales: FERREIRA, Dyna Mara Araújo Oliveira, COSTA, Yuri Martins, BONJARDIM, Leonardo Rigoldi, CONTI, Paulo César Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade De Odontologia De Bauru - USP 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232930/
https://www.ncbi.nlm.nih.gov/pubmed/34105694
http://dx.doi.org/10.1590/1678-7757-2020-0952
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author FERREIRA, Dyna Mara Araújo Oliveira
COSTA, Yuri Martins
BONJARDIM, Leonardo Rigoldi
CONTI, Paulo César Rodrigues
author_facet FERREIRA, Dyna Mara Araújo Oliveira
COSTA, Yuri Martins
BONJARDIM, Leonardo Rigoldi
CONTI, Paulo César Rodrigues
author_sort FERREIRA, Dyna Mara Araújo Oliveira
collection PubMed
description Stress is a contributing factor to painful temporomandibular disorders (TMD). Nevertheless, the underpinnings of this relationship are not fully understood. OBJECTIVE: To investigate the effects of acute mental stress on conditioned pain modulation (CPM) in TMD patients compared with healthy individuals. METHODOLOGY: Twenty women with chronic myofascial TMD diagnosed according to the RDC/TMD and 20 age-matched healthy women had the CPM assessed before and after a stressful task using the Paced Auditory Serial Addition Task (PASAT) in a single session. Subjective stress response was assessed with the aid of visual analog scale (VAS). Pressure pain threshold (PPT) on masseter muscle was the test stimulus (TS) and immersion of the participant’s hand on hot water was the conditioning stimulus (CS) - CPM-sequential paradigm. RESULTS: Healthy individuals reported PASAT are more stressful when compared with TMD patients and the stress task did not affect the CPM in neither group. Nonetheless, a negative correlation was observed between change in CPM and change in TS from baseline to post-stress session, which indicates that the greater the increase in PPT after the stress task, the greater was the decrease in CPM magnitude. The correlation was strong for healthy controls (r=- 0.72, p<0.001) and moderate for TMD patients (r=- 0.44, p=0.047). CONCLUSIONS: The correlation between the change in CPM and the TS change following the stress task may possibly indicate an overlapping pathway between stress-induced analgesia/hyperalgesia and descending pain inhibition.
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spelling pubmed-82329302021-06-28 Effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals FERREIRA, Dyna Mara Araújo Oliveira COSTA, Yuri Martins BONJARDIM, Leonardo Rigoldi CONTI, Paulo César Rodrigues J Appl Oral Sci Original Article Stress is a contributing factor to painful temporomandibular disorders (TMD). Nevertheless, the underpinnings of this relationship are not fully understood. OBJECTIVE: To investigate the effects of acute mental stress on conditioned pain modulation (CPM) in TMD patients compared with healthy individuals. METHODOLOGY: Twenty women with chronic myofascial TMD diagnosed according to the RDC/TMD and 20 age-matched healthy women had the CPM assessed before and after a stressful task using the Paced Auditory Serial Addition Task (PASAT) in a single session. Subjective stress response was assessed with the aid of visual analog scale (VAS). Pressure pain threshold (PPT) on masseter muscle was the test stimulus (TS) and immersion of the participant’s hand on hot water was the conditioning stimulus (CS) - CPM-sequential paradigm. RESULTS: Healthy individuals reported PASAT are more stressful when compared with TMD patients and the stress task did not affect the CPM in neither group. Nonetheless, a negative correlation was observed between change in CPM and change in TS from baseline to post-stress session, which indicates that the greater the increase in PPT after the stress task, the greater was the decrease in CPM magnitude. The correlation was strong for healthy controls (r=- 0.72, p<0.001) and moderate for TMD patients (r=- 0.44, p=0.047). CONCLUSIONS: The correlation between the change in CPM and the TS change following the stress task may possibly indicate an overlapping pathway between stress-induced analgesia/hyperalgesia and descending pain inhibition. Faculdade De Odontologia De Bauru - USP 2021-06-04 /pmc/articles/PMC8232930/ /pubmed/34105694 http://dx.doi.org/10.1590/1678-7757-2020-0952 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
FERREIRA, Dyna Mara Araújo Oliveira
COSTA, Yuri Martins
BONJARDIM, Leonardo Rigoldi
CONTI, Paulo César Rodrigues
Effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals
title Effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals
title_full Effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals
title_fullStr Effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals
title_full_unstemmed Effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals
title_short Effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals
title_sort effects of acute mental stress on conditioned pain modulation in temporomandibular disorders patients and healthy individuals
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232930/
https://www.ncbi.nlm.nih.gov/pubmed/34105694
http://dx.doi.org/10.1590/1678-7757-2020-0952
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