Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment

BACKGROUND: Hepatic platelet accumulation contributes to acetaminophen (APAP)-induced liver injury (AILI). However, little is known about the molecular pathways involved in platelet recruitment to the liver and whether targeting such pathways could attenuate AILI. METHODS: Mice were fasted overnight...

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Detalles Bibliográficos
Autores principales: Shan, Zhao, Li, Leike, Atkins, Constance Lynn, Wang, Meng, Wen, Yankai, Jeong, Jongmin, Moreno, Nicolas F, Feng, Dechun, Gui, Xun, Zhang, Ningyan, Lee, Chun Geun, Elias, Jack A, Lee, William M, Gao, Bin, Lam, Fong Wilson, An, Zhiqiang, Ju, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233036/
https://www.ncbi.nlm.nih.gov/pubmed/34110284
http://dx.doi.org/10.7554/eLife.68571

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