A20/Nrdp1 interaction alters the inflammatory signaling profile by mediating K48- and K63-linked polyubiquitination of effectors MyD88 and TBK1

A20 is a potent anti-inflammatory protein that mediates both inflammation and ubiquitination in mammals, but the related mechanisms are not clear. In this study, we performed mass spectrometry (MS) screening, gene ontology (GO) analysis, and coimmunoprecipitation (co-IP) in a lipopolysaccharide (LPS...

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Detalles Bibliográficos
Autores principales: Meng, Zhaoyou, Xu, Rui, Xie, Lexing, Wu, Yutong, He, Qian, Gao, Pan, He, Xiaohui, Chen, Qiong, Xie, Qi, Zhang, Jiqiang, Yang, Qingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233150/
https://www.ncbi.nlm.nih.gov/pubmed/34023381
http://dx.doi.org/10.1016/j.jbc.2021.100811

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