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Genotoxic risk in humans and acute toxicity in rats of a novel oral high-dose coenzyme Q10 oleogel

Coenzyme Q(10) (CoQ(10)) supplementation has demonstrated to be safe and effective in primary and secondary CoQ(10) deficiencies. Previously, we have designed a high-dose CoQ(10) oleogel (1 g/disk) with excipients used in quantities that do not represent any toxic risk. However, it was necessary to...

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Detalles Bibliográficos
Autores principales: Masotta, Natalia Ehrenhaus, Martinez-Perafan, Fabian, Carballo, Marta Ana, Gorzalczany, Susana Beatriz, Rojas, Ana M., Tripodi, Valeria P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233171/
https://www.ncbi.nlm.nih.gov/pubmed/34195014
http://dx.doi.org/10.1016/j.toxrep.2021.06.012