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On the origin of germ cell neoplasia in situ: Dedifferentiation of human adult Sertoli cells in cross talk with seminoma cells in vitro

Germ cell neoplasia in situ (GCNIS) is the noninvasive precursor of testicular germ cell tumors type II, the most common cancer in young men, which originates from embryonic germ cells blocked in their maturation. GCNIS is associated with impaired Sertoli cells (SCs) that express fetal keratin 18 (K...

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Detalles Bibliográficos
Autores principales: Fink, Cornelia, Baal, Nelli, Wilhelm, Jochen, Sarode, Poonam, Weigel, Roswitha, Schumacher, Valérie, Nettersheim, Daniel, Schorle, Hubert, Schröck, Carmen, Bergmann, Martin, Kliesch, Sabine, Kressin, Monika, Savai, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233172/
https://www.ncbi.nlm.nih.gov/pubmed/34153645
http://dx.doi.org/10.1016/j.neo.2021.05.008

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