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Discovery of cyclohexadepsipeptides with anti-Zika virus activities and biosynthesis of the nonproteinogenic building block (3S)-methyl-l-proline

The fungal cyclohexadepsipeptides destruxins (DTXs), isaridins (ISDs), and isariins (ISRs) are nonribosomal peptides whose structures include a 19-membered ring composed of five amino acid residues and one α- or β-hydroxy acid residue. These cyclohexadepsipeptides contain unusual nonproteinogenic am...

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Detalles Bibliográficos
Autores principales:	Yuan, Bochuan, Wu, Ziwei, Ji, Wei, Liu, Dong, Guo, Xiang, Yang, Donghui, Fan, Aili, Jia, Hongli, Ma, Ming, Lin, Wenhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233208/ https://www.ncbi.nlm.nih.gov/pubmed/34029593 http://dx.doi.org/10.1016/j.jbc.2021.100822

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