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Loss of PKA regulatory subunit 1α aggravates cardiomyocyte necrosis and myocardial ischemia/reperfusion injury

Reperfusion therapy, the standard treatment for acute myocardial infarction, can trigger necrotic death of cardiomyocytes and provoke ischemia/reperfusion (I/R) injury. However, signaling pathways that regulate cardiomyocyte necrosis remain largely unknown. Our recent genome-wide RNAi screen has ide...

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Detalles Bibliográficos
Autores principales:	Liu, Yuening, Chen, Jingrui, Xia, Peng, Stratakis, Constantine A., Cheng, Zhaokang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233231/ https://www.ncbi.nlm.nih.gov/pubmed/34087234 http://dx.doi.org/10.1016/j.jbc.2021.100850

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