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Aβ1-16 controls synaptic vesicle pools at excitatory synapses via cholinergic modulation of synapsin phosphorylation

Amyloid beta (Aβ) is linked to the pathology of Alzheimer’s disease (AD). At physiological concentrations, Aβ was proposed to enhance neuroplasticity and memory formation by increasing the neurotransmitter release from presynapse. However, the exact mechanisms underlying this presynaptic effect as w...

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Detalles Bibliográficos
Autores principales: Anni, Daniela, Weiss, Eva-Maria, Guhathakurta, Debarpan, Akdas, Yagiz Enes, Klueva, Julia, Zeitler, Stefanie, Andres-Alonso, Maria, Huth, Tobias, Fejtova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233295/
https://www.ncbi.nlm.nih.gov/pubmed/33864480
http://dx.doi.org/10.1007/s00018-021-03835-5