Cargando…
Aβ1-16 controls synaptic vesicle pools at excitatory synapses via cholinergic modulation of synapsin phosphorylation
Amyloid beta (Aβ) is linked to the pathology of Alzheimer’s disease (AD). At physiological concentrations, Aβ was proposed to enhance neuroplasticity and memory formation by increasing the neurotransmitter release from presynapse. However, the exact mechanisms underlying this presynaptic effect as w...
Autores principales: | Anni, Daniela, Weiss, Eva-Maria, Guhathakurta, Debarpan, Akdas, Yagiz Enes, Klueva, Julia, Zeitler, Stefanie, Andres-Alonso, Maria, Huth, Tobias, Fejtova, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233295/ https://www.ncbi.nlm.nih.gov/pubmed/33864480 http://dx.doi.org/10.1007/s00018-021-03835-5 |
Ejemplares similares
-
Development and Application of Automatized Routines for Optical Analysis of Synaptic Activity Evoked by Chemical and Electrical Stimulation
por: Guhathakurta, Debarpan, et al.
Publicado: (2022) -
Bassoon controls synaptic vesicle release via regulation of presynaptic phosphorylation and cAMP
por: Montenegro‐Venegas, Carolina, et al.
Publicado: (2022) -
Acid Sphingomyelinase Impacts Canonical Transient Receptor Potential Channels 6 (TRPC6) Activity in Primary Neuronal Systems
por: Zeitler, Stefanie, et al.
Publicado: (2020) -
Synapsins and the Synaptic Vesicle Reserve Pool: Floats or Anchors?
por: Zhang, Minchuan, et al.
Publicado: (2021) -
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD
por: Bauer, Claudia S., et al.
Publicado: (2022)