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The role of CYP2D in rat brain in methamphetamine-induced striatal dopamine and serotonin release and behavioral sensitization

RATIONALE: Cytochrome P450 2D (CYP2D) enzymes metabolize many addictive drugs, including methamphetamine. Variable CYP2D metabolism in the brain may alter CNS drug/metabolite concentrations, consequently affecting addiction liability and neuropsychiatric outcomes; components of these can be modeled...

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Detalles Bibliográficos
Autores principales:	Stocco, Marlaina R., El-Sherbeni, Ahmed A., Zhao, Bin, Novalen, Maria, Tyndale, Rachel F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233297/ https://www.ncbi.nlm.nih.gov/pubmed/33649968 http://dx.doi.org/10.1007/s00213-021-05808-9

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