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Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya
Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observe...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233334/ https://www.ncbi.nlm.nih.gov/pubmed/34172732 http://dx.doi.org/10.1038/s41467-021-24062-3 |
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| author | Adetifa, Ifedayo M. O. Uyoga, Sophie Gitonga, John N. Mugo, Daisy Otiende, Mark Nyagwange, James Karanja, Henry K. Tuju, James Wanjiku, Perpetual Aman, Rashid Mwangangi, Mercy Amoth, Patrick Kasera, Kadondi Ng’ang’a, Wangari Rombo, Charles Yegon, Christine Kithi, Khamisi Odhiambo, Elizabeth Rotich, Thomas Orgut, Irene Kihara, Sammy Bottomley, Christian Kagucia, Eunice W. Gallagher, Katherine E. Etyang, Anthony Voller, Shirine Lambe, Teresa Wright, Daniel Barasa, Edwine Tsofa, Benjamin Bejon, Philip Ochola-Oyier, Lynette I. Agweyu, Ambrose Scott, J. Anthony G. Warimwe, George M. |
| author_facet | Adetifa, Ifedayo M. O. Uyoga, Sophie Gitonga, John N. Mugo, Daisy Otiende, Mark Nyagwange, James Karanja, Henry K. Tuju, James Wanjiku, Perpetual Aman, Rashid Mwangangi, Mercy Amoth, Patrick Kasera, Kadondi Ng’ang’a, Wangari Rombo, Charles Yegon, Christine Kithi, Khamisi Odhiambo, Elizabeth Rotich, Thomas Orgut, Irene Kihara, Sammy Bottomley, Christian Kagucia, Eunice W. Gallagher, Katherine E. Etyang, Anthony Voller, Shirine Lambe, Teresa Wright, Daniel Barasa, Edwine Tsofa, Benjamin Bejon, Philip Ochola-Oyier, Lynette I. Agweyu, Ambrose Scott, J. Anthony G. Warimwe, George M. |
| author_sort | Adetifa, Ifedayo M. O. |
| collection | PubMed |
| description | Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality. |
| format | Online Article Text |
| id | pubmed-8233334 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-82333342021-07-09 Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya Adetifa, Ifedayo M. O. Uyoga, Sophie Gitonga, John N. Mugo, Daisy Otiende, Mark Nyagwange, James Karanja, Henry K. Tuju, James Wanjiku, Perpetual Aman, Rashid Mwangangi, Mercy Amoth, Patrick Kasera, Kadondi Ng’ang’a, Wangari Rombo, Charles Yegon, Christine Kithi, Khamisi Odhiambo, Elizabeth Rotich, Thomas Orgut, Irene Kihara, Sammy Bottomley, Christian Kagucia, Eunice W. Gallagher, Katherine E. Etyang, Anthony Voller, Shirine Lambe, Teresa Wright, Daniel Barasa, Edwine Tsofa, Benjamin Bejon, Philip Ochola-Oyier, Lynette I. Agweyu, Ambrose Scott, J. Anthony G. Warimwe, George M. Nat Commun Article Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality. Nature Publishing Group UK 2021-06-25 /pmc/articles/PMC8233334/ /pubmed/34172732 http://dx.doi.org/10.1038/s41467-021-24062-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
| spellingShingle | Article Adetifa, Ifedayo M. O. Uyoga, Sophie Gitonga, John N. Mugo, Daisy Otiende, Mark Nyagwange, James Karanja, Henry K. Tuju, James Wanjiku, Perpetual Aman, Rashid Mwangangi, Mercy Amoth, Patrick Kasera, Kadondi Ng’ang’a, Wangari Rombo, Charles Yegon, Christine Kithi, Khamisi Odhiambo, Elizabeth Rotich, Thomas Orgut, Irene Kihara, Sammy Bottomley, Christian Kagucia, Eunice W. Gallagher, Katherine E. Etyang, Anthony Voller, Shirine Lambe, Teresa Wright, Daniel Barasa, Edwine Tsofa, Benjamin Bejon, Philip Ochola-Oyier, Lynette I. Agweyu, Ambrose Scott, J. Anthony G. Warimwe, George M. Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya |
| title | Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya |
| title_full | Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya |
| title_fullStr | Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya |
| title_full_unstemmed | Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya |
| title_short | Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya |
| title_sort | temporal trends of sars-cov-2 seroprevalence during the first wave of the covid-19 epidemic in kenya |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233334/ https://www.ncbi.nlm.nih.gov/pubmed/34172732 http://dx.doi.org/10.1038/s41467-021-24062-3 |
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