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Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information

Semantic categorization is a fundamental ability in language as well as in interaction with the environment. However, it is unclear what cognitive and neural basis generates this flexible and context dependent categorization of semantic information. We performed behavioral and fMRI experiments with...

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Autores principales: Matsumoto, Atsushi, Soshi, Takahiro, Fujimaki, Norio, Ihara, Aya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233387/
https://www.ncbi.nlm.nih.gov/pubmed/34172800
http://dx.doi.org/10.1038/s41598-021-92726-7
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author Matsumoto, Atsushi
Soshi, Takahiro
Fujimaki, Norio
Ihara, Aya S.
author_facet Matsumoto, Atsushi
Soshi, Takahiro
Fujimaki, Norio
Ihara, Aya S.
author_sort Matsumoto, Atsushi
collection PubMed
description Semantic categorization is a fundamental ability in language as well as in interaction with the environment. However, it is unclear what cognitive and neural basis generates this flexible and context dependent categorization of semantic information. We performed behavioral and fMRI experiments with a semantic priming paradigm to clarify this. Participants conducted semantic decision tasks in which a prime word preceded target words, using names of animals (mammals, birds, or fish). We focused on the categorization of unique marine mammals, having characteristics of both mammals and fish. Behavioral experiments indicated that marine mammals were semantically closer to fish than terrestrial mammals, inconsistent with the category membership. The fMRI results showed that the left anterior temporal lobe was sensitive to the semantic distance between prime and target words rather than category membership, while the left ventrolateral prefrontal cortex was sensitive to the consistency of category membership of word pairs. We interpreted these results as evidence of existence of dual processes for semantic categorization. The combination of bottom-up processing based on semantic characteristics in the left anterior temporal lobe and top-down processing based on task and/or context specific information in the left ventrolateral prefrontal cortex is required for the flexible categorization of semantic information.
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spelling pubmed-82333872021-07-06 Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information Matsumoto, Atsushi Soshi, Takahiro Fujimaki, Norio Ihara, Aya S. Sci Rep Article Semantic categorization is a fundamental ability in language as well as in interaction with the environment. However, it is unclear what cognitive and neural basis generates this flexible and context dependent categorization of semantic information. We performed behavioral and fMRI experiments with a semantic priming paradigm to clarify this. Participants conducted semantic decision tasks in which a prime word preceded target words, using names of animals (mammals, birds, or fish). We focused on the categorization of unique marine mammals, having characteristics of both mammals and fish. Behavioral experiments indicated that marine mammals were semantically closer to fish than terrestrial mammals, inconsistent with the category membership. The fMRI results showed that the left anterior temporal lobe was sensitive to the semantic distance between prime and target words rather than category membership, while the left ventrolateral prefrontal cortex was sensitive to the consistency of category membership of word pairs. We interpreted these results as evidence of existence of dual processes for semantic categorization. The combination of bottom-up processing based on semantic characteristics in the left anterior temporal lobe and top-down processing based on task and/or context specific information in the left ventrolateral prefrontal cortex is required for the flexible categorization of semantic information. Nature Publishing Group UK 2021-06-25 /pmc/articles/PMC8233387/ /pubmed/34172800 http://dx.doi.org/10.1038/s41598-021-92726-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Matsumoto, Atsushi
Soshi, Takahiro
Fujimaki, Norio
Ihara, Aya S.
Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information
title Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information
title_full Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information
title_fullStr Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information
title_full_unstemmed Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information
title_short Distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information
title_sort distinctive responses in anterior temporal lobe and ventrolateral prefrontal cortex during categorization of semantic information
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233387/
https://www.ncbi.nlm.nih.gov/pubmed/34172800
http://dx.doi.org/10.1038/s41598-021-92726-7
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