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Modulation of microglial phenotypes by dexmedetomidine through TREM2 reduces neuroinflammation in heatstroke

No FDA approved pharmacological therapy is available to reduce neuroinflammation following heatstroke. Previous studies have indicated that dexmedetomidine (DEX) could protect against inflammation and brain injury in various inflammation-associated diseases. However, no one has tested whether DEX ha...

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Detalles Bibliográficos
Autores principales: Li, Ping, Shen, Tingting, Luo, Xue, Yang, Ju, Luo, Zhen, Tan, Yulong, He, Genlin, Wang, Zeze, Yu, Xueting, Wang, Ying, Yang, Xuesen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233427/
https://www.ncbi.nlm.nih.gov/pubmed/34172807
http://dx.doi.org/10.1038/s41598-021-92906-5