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Modulation of microglial phenotypes by dexmedetomidine through TREM2 reduces neuroinflammation in heatstroke
No FDA approved pharmacological therapy is available to reduce neuroinflammation following heatstroke. Previous studies have indicated that dexmedetomidine (DEX) could protect against inflammation and brain injury in various inflammation-associated diseases. However, no one has tested whether DEX ha...
Autores principales: | Li, Ping, Shen, Tingting, Luo, Xue, Yang, Ju, Luo, Zhen, Tan, Yulong, He, Genlin, Wang, Zeze, Yu, Xueting, Wang, Ying, Yang, Xuesen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233427/ https://www.ncbi.nlm.nih.gov/pubmed/34172807 http://dx.doi.org/10.1038/s41598-021-92906-5 |
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