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Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries

There are limited data pertaining to current practices in timing of surgical decompression for acute thoracolumbar spinal cord injury (SCI). We conducted a retrospective cohort study to evaluate variability in timing between- and within-trauma centers in North America; and to identify patient- and h...

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Autores principales: Badhiwala, Jetan H., Lebovic, Gerald, Balas, Michael, da Costa, Leodante, Nathens, Avery B., Fehlings, Michael G., Wilson, Jefferson R., Witiw, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233434/
https://www.ncbi.nlm.nih.gov/pubmed/34172757
http://dx.doi.org/10.1038/s41598-021-92310-z
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author Badhiwala, Jetan H.
Lebovic, Gerald
Balas, Michael
da Costa, Leodante
Nathens, Avery B.
Fehlings, Michael G.
Wilson, Jefferson R.
Witiw, Christopher D.
author_facet Badhiwala, Jetan H.
Lebovic, Gerald
Balas, Michael
da Costa, Leodante
Nathens, Avery B.
Fehlings, Michael G.
Wilson, Jefferson R.
Witiw, Christopher D.
author_sort Badhiwala, Jetan H.
collection PubMed
description There are limited data pertaining to current practices in timing of surgical decompression for acute thoracolumbar spinal cord injury (SCI). We conducted a retrospective cohort study to evaluate variability in timing between- and within-trauma centers in North America; and to identify patient- and hospital-level factors associated with treatment delay. Adults with acute thoracolumbar SCI who underwent decompressive surgery within five days of injury at participating trauma centers in the American College of Surgeons Trauma Quality Improvement Program were included. Mixed-effects regression with a random intercept for trauma center was used to model the outcome of time to surgical decompression and assess risk-adjusted variability in surgery timeliness across centers. 3,948 patients admitted to 214 TQIP centers were eligible. 28 centers were outliers, with a significantly shorter or longer time to surgery than average. Case-mix and hospital characteristics explained < 1% of between-hospital variability in surgical timing. Moreover, only 7% of surgical timing variability within-centers was explained by case-mix characteristics. The adjusted intraclass correlation coefficient of 12% suggested poor correlation of surgical timing for patients with similar characteristics treated at the same center. These findings support the need for further research into the optimal timing of surgical intervention for thoracolumbar SCI.
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spelling pubmed-82334342021-07-06 Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries Badhiwala, Jetan H. Lebovic, Gerald Balas, Michael da Costa, Leodante Nathens, Avery B. Fehlings, Michael G. Wilson, Jefferson R. Witiw, Christopher D. Sci Rep Article There are limited data pertaining to current practices in timing of surgical decompression for acute thoracolumbar spinal cord injury (SCI). We conducted a retrospective cohort study to evaluate variability in timing between- and within-trauma centers in North America; and to identify patient- and hospital-level factors associated with treatment delay. Adults with acute thoracolumbar SCI who underwent decompressive surgery within five days of injury at participating trauma centers in the American College of Surgeons Trauma Quality Improvement Program were included. Mixed-effects regression with a random intercept for trauma center was used to model the outcome of time to surgical decompression and assess risk-adjusted variability in surgery timeliness across centers. 3,948 patients admitted to 214 TQIP centers were eligible. 28 centers were outliers, with a significantly shorter or longer time to surgery than average. Case-mix and hospital characteristics explained < 1% of between-hospital variability in surgical timing. Moreover, only 7% of surgical timing variability within-centers was explained by case-mix characteristics. The adjusted intraclass correlation coefficient of 12% suggested poor correlation of surgical timing for patients with similar characteristics treated at the same center. These findings support the need for further research into the optimal timing of surgical intervention for thoracolumbar SCI. Nature Publishing Group UK 2021-06-25 /pmc/articles/PMC8233434/ /pubmed/34172757 http://dx.doi.org/10.1038/s41598-021-92310-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Badhiwala, Jetan H.
Lebovic, Gerald
Balas, Michael
da Costa, Leodante
Nathens, Avery B.
Fehlings, Michael G.
Wilson, Jefferson R.
Witiw, Christopher D.
Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries
title Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries
title_full Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries
title_fullStr Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries
title_full_unstemmed Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries
title_short Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries
title_sort variability in time to surgery for patients with acute thoracolumbar spinal cord injuries
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233434/
https://www.ncbi.nlm.nih.gov/pubmed/34172757
http://dx.doi.org/10.1038/s41598-021-92310-z
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