The Impact of Purifying and Background Selection on the Inference of Population History: Problems and Prospects

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Current procedures for inferring population history generally assume complete neutrality—that is, they neglect both direct selection and the effects of selection on linked sites. We here examine how the presence of direct purifying selection and background selection may bias demographic inference by...

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Detalles Bibliográficos
Autores principales: Johri, Parul, Riall, Kellen, Becher, Hannes, Excoffier, Laurent, Charlesworth, Brian, Jensen, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233493/
https://www.ncbi.nlm.nih.gov/pubmed/33591322
http://dx.doi.org/10.1093/molbev/msab050

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